This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

The NWO Executive Board has approved seventeen groundbreaking grant applications aimed at advancing fundamental, high-impact scientific research.

Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers.

The new technology – Cleavage Under Targeted Accessible Chromatin (CUTAC) – focuses on small, fragmented DNA non-coding ...

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately ...

Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer ...

Mainly distributed in the nucleus and cytoplasm of cells, lncRNAs are the transcription products of RNA polymerase II. LncRNAs have been classified based on the lengths of the coded transcripts as ...

It both stabilizes a critical protein called RNA Polymerase II—the molecular engine of gene transcription—and reshapes the structure of chromatin, the tightly packed form of DNA, to activate ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...