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Evidence-informed decision-making (EIDM) refers to the systematic and transparent process of identifying, appraising and mobilising the best available evidence to inform the development of safe and ...

Objective To estimate associations between trivalent influenza vaccination and COVID-19 mortality as well as severe clinical outcomes among hospitalised patients. Design Retrospective observational ...

Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

Objectives Cancer overdiagnosis is a polarizing topic, with much disagreement on its drivers, magnitude, and implications. Overdiagnosis is also complex, as various factors interact to influence said ...

As a heart surgeon, you regularly perform aortic valve replacement, using a median sternotomy technique. However, you are aware that less-invasive options are available, and you wonder whether these ...

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...