The investigation of children with early developmental impairment (EDI) is challenging in terms of selecting investigations and supporting families through the diagnostic pathway. Modern genomic ...

CK, creatine kinase; DAT, direct antiglobulin test; EMA, antiendomysial antibody; LDH, lactate dehydrogenase.; TSH, thyroid stimulating hormone; tTG, tissue ...

Table 1 Approximate costs for commonly used investigations in children with chronic abdominal pain ...

Central venous catheter (CVC) tip cultures are useful in the assessment of a patient with a potential catheter-related bloodstream infection (CRBSI). However, these results can be misleading ...

Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatic disease with significant long-term morbidity and mortality. Major advances have taken place in recent years in our ...

### Design Randomised controlled trial. ### Allocation Computer-generated random schedule stratified by age and centre. ### Blinding Care givers and assessors blind to treatment. Blinded medications ...

Nutritional content of meal plansTable 1 Nutritional content of meal plans ...

Design : Randomised controlled trial. Allocation : Randomisation was done by university staff. Allocation was concealed using sealed envelopes that were sequentially numbered. Blinding : All patients, ...

Table 6 Clinical signs and symptoms typical of upper airway obstruction at different anatomical levels ...

Recurrent aphthous stomatitis on palate.Figure 3 Recurrent aphthous stomatitis on palate.

Infection Sepsis creates an increased metabolic demand. The infant may be unable to meet the increased oxygen requirements of the tissues leading to peripheral vasoconstriction and cyanosis. In ...