May 6, 2024 · Glioblastoma multiforme (GBM) comprises glioma's most malignant and pervasive subtype. GBM is the most common primary brain tumor in adults, accounting for 45.2% of primary malignant brain and central nervous system (CNS) tumors.

Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain tumor in adults. Despite important advances in understanding the molecular pathogenesis and biology of this tumor in the past decade, the prognosis for GBM patients remains poor.

Glioblastoma (GBM), the most lethal primary brain malignancy, is divided into histological (hist-GBM) and molecular (mol-GBM) subtypes according to the 2021 World Health Organization classification of central nervous system tumors.

Glioblastoma multiforme is a central nervous system tumor of grade IV histological malignancy according to the WHO classification. Over 90% of diagnosed glioblastomas multiforme cases are primary gliomas, arising from normal glial cells through multistep oncogenesis.

Glioblastoma a very common malignant primary brain tumour in adults. It has a very poor prognosis. It was previously known as glioblastoma multiforme, abbreviated GBM.

Dec 26, 2020 · Previously named as “glioblastoma multiforme” due to cut section being variegated (yellowish necrotic central area, grayish peripheral rim, recent and old hemorrhage, cysts due to liquefied necrotic tumor tissue) and having diverse histological features

Feb 1, 2024 · Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain tumor in adults. Despite important advances in understanding the molecular pathogenesis and biology of this tumor in the past decade, the prognosis for GBM patients remains poor.

Jan 1, 2009 · Glioblastomas have been assigned the highest grade (grade IV) based on the presence of histopathological features of tumor cell necrosis including geographic necrosis and/or microvascular proliferations (angiogenesis) within the tumor.

May 1, 2021 · Histopathologically, GBM consists of varying proportions of spindle cells, embedded within a fibrillary (eosinophilic, stringy) network (Fig. 5.1a). The cells are enlarged, irregular in morphology, with hyperchromasia and pleomorphism [1]. Tumor cells can also appear variably shaped, including rounded, giant, or even bizarre [2] (Fig. 5.1b).

Glioblastoma multiforme is a central nervous system tumor of grade IV histological malignancy according to the WHO classification. Over 90% of diagnosed glioblastomas multiforme cases are primary gliomas, arising from normal glial cells through multistep oncogenesis.