Dec 1, 2018 · What Is Axial Psoriatic Arthritis? Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease that has 5 disease domains: peripheral arthritis, axial disease, dactylitis, enthesitis, and skin and nail disease 1.

Dec 29, 2020 · Here is a look at three general phases of psoriatic arthritis and what each one is like. Pre-clinical Psoriatic Arthritis. Psoriatic arthritis doesn’t arrive completely out of nowhere. People who are ultimately diagnosed with PsA can look back and identify symptoms that occurred for months and years beforehand.

May 6, 2022 · The axial phenotype of psoriatic arthritis (axPsA) is an excellent example of a major controversy in rheumatology that has become the focus of attention because of the emergence of new therapies with different mechanisms of action for alleviating joint inflammation.

Jan 7, 2024 · Psoriatic arthritis, occurring in approximately 20% of individuals with psoriasis, is a chronic inflammatory arthritis intricately linked to psoriatic arthritis. This aggressive condition is characterized by potential significant morbidity and compromised quality of life.

Psoriatic arthritis—a heterogeneous, inflammatory, musculoskeletal disease that can cause permanent damage to both peripheral and axial joints—is the most common comorbidity of psoriasis. Axial disease occurs in 25% to 70% of patients with PsA, with some patients exclusively experiencing axial joint involvement.

Axial involvement may occur in up to 50% of patients with PsA (axPsA), causing inflammatory back pain, stiffness and changes on imaging. Whether axial SpA (axSpA) with psoriasis represents a distinct entity than axPsA is a matter of debate, since similarities and differences have been reported in terms of clinical expression and imaging.

Dec 17, 2024 · Axial inflammation in psoriatic arthritis (axPsA) occurs in up to 40% of patients with PsA. The clinical, radiographic and genetic phenotype of axPsA differs from that seen in ankylosing spondylitis. This alternative phenotype, which may also be seen in AS, may respond differently to treatment.

Jul 30, 2021 · Data from the Corrona Psoriatic Arthritis/Spondyloarthritis registry have indicated that among patients with PsA, axial involvement was associated with significantly worse disease, including an increased risk for moderate to severe psoriasis, higher disease activity, and a greater effect on quality of life. 6

Feb 1, 2023 · Results The systematic review of the literature showed that new biologic and targeted synthetic disease-modifying antirheumatic drug classes, namely interleukin (IL)-17A and Janus kinase inhibitors, could be considered for the treatment of axPsA.

Aug 1, 2021 · In this review, we summarize the clinical presentation, imaging characteristics, differential diagnoses, treatment options, and prognosis of axial PsA, with the aim of increasing rheumatologists’ knowledge of this phenotype of PsA and thereby aiding its optimal management.