A large-scale binding and functional map of human RNA-binding …
Jul 29, 2020 · Here we introduce a new data set of RNA elements in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the Encyclopedia of DNA …
A brave new world of RNA-binding proteins - Nature
Jan 17, 2018 · RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one or multiple globular RNA-binding domains (RBDs) and change the fate or function …
RNA-binding proteins in human genetic disease - Nature
Nov 24, 2020 · Following the description of RNA interactome capture (RIC), a plethora of unbiased, high-throughput studies have ensued that identify RNA-binding proteins (RBPs) and …
RNA-binding proteins - Latest research and news - Nature
RNA-binding proteins are proteins that bind to ribonucleic acid (RNA) molecules, are generally found in the cytoplasm and nucleus, and are important in forming ribonucleoproteins (RNPs).
RNA-binding proteins: modular design for efficient function
Many RNA-binding proteins have modular structures and are composed of multiple repeats of just a few basic domains that are arranged in various ways to satisfy their diverse functional …
Methods to study RNA–protein interactions - Nature
Feb 25, 2019 · Recent progress has expanded the number of methods for studying RNA–protein interactions in two general categories: approaches that characterize proteins bound to an RNA …
The structure, function and evolution of proteins that bind DNA …
Oct 1, 2014 · Such DNA- and RNA-binding proteins (DRBPs) have unique functional characteristics that stem from their specific structural features; these developed early in …
RNA-binding proteins control gene expression and cell fate in the ...
Jan 18, 2018 · RNA-binding proteins (RBPs) are essential for the development and function of the immune system. They interact dynamically with RNA to control its biogenesis and turnover by …
RNA-binding proteins | Nature Communications
ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of …
Phase separation of RNA-binding protein promotes polymerase
Dec 16, 2021 · Here we find that RNA-binding proteins (RBPs) constitute half of the chromatin proteome in embryonic stem cells (ESCs), some being colocalized with RNA polymerase (Pol) …